Lack of Predictive Value of Isolating Coagulase-Negative Staphylococci from Blood Cultures

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Lack of predictive value of isolating coagulase-negative staphylococci from blood cultures.

SIR-Berwaldt et al. [1] reported that, in their intensive care unit, 26.4% of patients whose Isolator (Wampole Laboratories, Cranbury, NJ) blood cultures yielded coagulase-negative staphylococci (CNS) had true bloodstream infections. These authors defined infection according to a set of criteria. They then analyzed their findings to determine the variables associated with infection. A basic fau...

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Predictive value of blood cultures positive for coagulase-negative staphylococci: implications for patient care and health care quality assurance.

Interpretation of blood cultures that are positive for coagulase-negative staphylococci (CoNS) is often difficult. Predictive values for blood cultures positive for CoNS in patients with a central vascular line in place were calculated using the following rates: true bacteremia, 3%; blood culture contamination, 2%; detection of bacteremia, 80%; and catheter colonization, 2% (for blood samples o...

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Epidemiology and significance of coagulase-negative staphylococci isolated in blood cultures from critically ill adult patients.

BACKGROUND Little published data are available on the epidemiology and significance of coagulase-negative staphylococci (CoNS) in blood culture isolates among critically ill adult patients. OBJECTIVES To describe the epidemiology and frequency of CoNS blood culture isolates in critically ill adults, and investigate the association between time to positivity (TTP) of blood cultures and number ...

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Coagulase-Negative Staphylococci Isolated from Blood Cultures: Contamination or Infection? Atherapeutic and Diagnosticchallenge

The possibility of contamination of the blood cultures, particularly by Coagulase-Negative Staphylococci (CoNS), is one of the challenges in microbiology. We performed a study from 2010 to 2015 to evaluate the percentage of CoNS arising from probable contamination and the percentage of CoNS probably responsible for sepsis. Additionally, we analysed susceptibility to antibiotics of all found mic...

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Coagulase-negative staphylococci strains resistant to oxacillin isolated from neonatal blood cultures

Coagulase-negative staphylococci (CoNS) are the microorganisms most frequently isolated from clinical samples and are commonly found in neonatal blood cultures. Oxacillin is an alternative treatment of choice for CoNS infections; however, resistance to oxacillin can have a substantial impact on healthcare by adversely affecting morbidity and mortality. The objective of this study was to detect ...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 1996

ISSN: 1058-4838,1537-6591

DOI: 10.1093/clinids/23.2.412